Before I Forget...

a study in the latest issue of Neurology reports that scientists have had some success with the COGNIShunt implant, which drains cerebrospinal fluid continuously from around the brain into the abdominal area. this fluid is recirculated much less frequently in alzheimer's patients than in a healthy person, and researchers have theorized that this limited CSF turnover may contribute to the buildup of plaques and neurofibrillary tangles.

alzheimer's is the cause of half of all dementia in older people. 20% of those over 80 will suffer from alzheimer's, 30% of those who live to the age of 90 will. as the aged population in the u.s. becomes larger than ever, it is likely that we will see more victims of this disease than ever before. as the research focus falls more toward treating the diseases of old age, it is exciting to imagine that not too far into the future we will find ways to prevent, treat, and even cure dementia.

i first read about the Neurology article in the USA Today on Wednesday, 23 Oct.
Read the article: Assessment of low-flow CSF drainage as a treatment for AD. Neurology 2002;59:1139-1145 Š2002 American Academy of Neurology

Sunday 27-Oct-02

The fact that you are reading these articles for entertainment makes you a way smarter person than myself. I play pool online or listen to rap music. Where did I go wrong?

posted by: jon on Monday 28-Oct-02

Question: Does the body produce a steady stream of spinal fluid, or is it the circulation of the fluid that keeps it kinda fresh? In moving it with the shunt implant, is it moving the fluid to a place where it is drained off, or is it put back into the spinal area further down creating an artificial cycle? I doubt I'm making sense. Still, I am curious.

posted by: Fraser on Monday 28-Oct-02

the body (the brain) produces CSF every day, quite a lot of it. the circulation of the fluid it when it moves from there outward to the spine and periphery. But in hydrocephalus and other ailments it acumulates in and around the brain, creating pressure, which in turn causes all kinds of problems. A shunt is exactly what it sounds like: it shunts the excess fluid away from the site and typically down into the abdomen where it is easily absorbed (CSF is mostly water).

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